1.
An Esp Pediatr
; 47(3): 334, 1997 Sep.
Artigo
em Espanhol
| MEDLINE
| ID: mdl-9499295
2.
An Esp Pediatr
; 35(1): 71-2, 1991 Jul.
Artigo
em Espanhol
| MEDLINE
| ID: mdl-1772179
3.
An Esp Pediatr
; 33(1): 58-60, 1990 Jul.
Artigo
em Espanhol
| MEDLINE
| ID: mdl-2252289
RESUMO
Homozygous familiar hypercholesterolemia (FH) is a serious inherited disease caused by a genetic defect in the cell surface receptor that controls the degradation of low density lipoprotein (LDL). These patients often have myocardial infarction in their teens or early adulthood and are usually unresponsive to drugs. Recently it has been reported promising results using combined drugs regimens in patients with residual receptor activity. We report a new additional patient with receptor-defective homozygous FH treated with a combination of lovastatin and cholestyramine. The cholesterol levels were reduced in a 67% and there were adverse events related to treatment during a 7 month period of follow-up.
Assuntos
Resina de Colestiramina/uso terapêutico , Hiperlipoproteinemia Tipo II/genética , Lovastatina/uso terapêutico , Pré-Escolar , Quimioterapia Combinada , Homozigoto , Humanos , Hiperlipoproteinemia Tipo II/tratamento farmacológico , Masculino
4.
An Esp Pediatr
; 29(2): 181-2, 1988 Aug.
Artigo
em Espanhol
| MEDLINE
| ID: mdl-3056153
5.
An Esp Pediatr
; 25 Suppl 26: 7-11, 1986 Oct.
Artigo
em Espanhol
| MEDLINE
| ID: mdl-3826935